About The Dose

I'm Doug Mitchell, a 40-year-old data analyst who got tired of being overweight and scared of GLP-1 side effects. After 1,000+ hours of research, I'm sharing evidence-based microdosing protocols that actually work.

The Mission

I woke up one day and was fed up.

40 pounds overweight at 40. Nothing working anymore.

I vowed to make a change, and here we are.

The GLP-1 Discovery

I kept hearing about these peptides everywhere - biohacking forums, friends, podcasts.

But I was scared. These drugs felt too new, too experimental.

So I Did What I Always Do - I Obsessed

1,000+ hours of research later, here's what I discovered:

The minimum effective dose approach works better for most people.

Not because I say so. Because the data says so.

What You'll Actually Find Here

Real Research, Real Numbers

Every protocol comes with:

  • Links to actual studies
  • Calculations you can verify
  • Community data from 5,000+ Reddit posts and forum discussions
  • Honest notes about what we don't know yet

Current compounds I track:

  • Tirzepatide (Mounjaro®, Zepbound®)
  • Semaglutide (Ozempic®, Wegovy®)
  • Retatrutide (emerging research)

Tools That Actually Work

  • Microdose Calculator: Because 5 units ≠ 5mg
  • Reconstitution Guide: Step-by-step, no confusion
  • Protocol Builder: Your personalized titration schedule
  • Side Effect Tracker: Know what's normal, what's not

The Minimum Effective Dose Philosophy

Tim Ferriss taught me something 15 years ago that changed everything: the minimum effective dose.

More isn't better. Better is better.

For GLP-1s, this means:

  • Start at 1/10th the standard trial dose
  • Titrate based on YOUR response
  • Track everything
  • Adjust based on data, not dogma
  • Your pancreas took years to get here - give it months to heal

Three Patterns I Keep Seeing

  1. People starting too high get wrecked by side effects
  2. Slow titration works just as well with 80% fewer issues
  3. Nobody's teaching the actual math of dosing

That's why this site exists.

Who This Is Really For

People like me who are:

  • Scared but ready to try
  • Tired of one-size-fits-all protocols
  • Data nerds who want to see the evidence
  • Currently suffering on standard doses
  • Looking for a smarter approach

Not for:

  • People who want medical advice (I'm not a doctor)
  • Quick fix seekers (this takes patience)
  • Anyone unwilling to track their data

The Uncomfortable Truth

I share everything. Including:

  • My current weight (still working on it)
  • Failed experiments (plenty of those)
  • Dosing mistakes I've made
  • Side effects I've experienced

Because real data beats perfect theory every time.

Medical Reality Check

I am not a doctor. This is not medical advice.

Everything here is educational. You need a real doctor to:

  • Prescribe medications
  • Monitor your health
  • Adjust your protocol
  • Handle complications

I just provide the math and the research.

Full Transparency

Yes, I have affiliate relationships:

  • Research compound companies
  • Concierge physicians
  • Function Health (lab testing)

No, I won't recommend garbage for a commission.

This is a hobby. My morals matter more than affiliate revenue.

The Data-Driven Promise

  1. Every claim has a source - No "trust me bro" science
  2. Updates when research changes - Science evolves
  3. Community data matters - Real world > lab conditions
  4. Free tools forever - Knowledge should be accessible

Join 500+ Optimizers

The Dose newsletter delivers:

  • New research (translated to English)
  • Protocol updates that actually work
  • Tool improvements
  • Community insights
  • My ongoing experiment results

Zero fluff. Just data.

Let's Connect

Found an error? Have data to share? Questions about the research?

[email protected]

I read everything. I respond to most within 48 hours.

The Dose started because I got tired of being overweight, scared of side effects, and frustrated by the lack of practical information. 1,000 hours of research later, I'm sharing what actually works. Because if I needed this data, you probably do too.

- Doug Mitchell, 40-year-old data analyst turned GLP-1 research obsessive

The content on The Dose is for informational and educational purposes only. It is not intended to be a substitute for professional medical advice, diagnosis, or treatment.

Always seek the advice of your physician or other qualified health provider with any questions you may have regarding a medical condition or treatment. Never disregard professional medical advice or delay in seeking it because of something you have read on this website.

The use of any information provided on this site is solely at your own risk. Doug Mitchell and The Dose will not be liable for any losses and/or damages in connection with the use of our website or the information provided.

GLP-1 agonists are prescription medications with potential risks and side effects. Individual results may vary. What works for one person may not work for another. This site shares research and personal experience, not medical recommendations.

By using this site, you acknowledge that you have read, understood, and agree to be bound by these terms.